"Puzzle Piece" Houses

Concept of creating customizable program pieces.. bedroom, living room, kitchen, bathroom, etc and designing them in a way to be able to be assembled in multiple layouts like a "unit" puzzle OR having pre-created units designed to suit most needs.

Different configurations of unit layouts with standard sized "pieces"

These could then be arranged on site relative to each other w/ respect to siting elements and could integrate with the site through added on landscape elements.

Unit aggregation - lacking reference to site, creation of unique environments.

Unit aggregation - variable unit shape/size - prefab complete units stacked together (no thought to MEP systems/distribution)

Moshe Safdie's Habitat 67 as prefab aggregated housing - creates unique spaces out of similar shaped objects based on layout. 

-- If the site is being created through the destruction of abandoned homes/leveling lots - how can the buildings react to the site without creating a fully "designed" environment?

-- How can units practically be stuck together without creating "boxes"?  Is this desirable?